is caused by a dominant gene and is believed to have originated
the current GCCF registration policies bar Persians from the pedigrees
of most breeds this was not always so. A study of old pedigrees
will often reveal the most surprising breeds in the background,
together with unregistered cats which may have been of any origin.
the presence of a Persian, or of a breed which is at higher risk,
in the background of any breed could possibly mean that the gene
for AD-PKD was introduced into that gene pool, there is a risk that
AD-PKD could be present in many different breeds.
those breeds where certain colours of Persians are permitted as
an outcross breed, it would be worth considering amending registration
policies to insist that only Persians which have been screened
clear of AD-PKD may be used as outcrosses, thus avoiding further
introductions of the gene.
All Persian breeds have a high risk, although it is somewhat lower
in Chinchillas and Golden Persians than in other colours.
The regular matings to Persians make this a high risk breed in
the same category as Persians.
British Shorthairs (BSH)
AD-PKD has been identified in BSH cats in the UK. The incidence appears to be lower than in Persian and Exotic Shorthaired cats but nonetheless pre-breeding testing is recommended for all BSH cats in order to prevent the disease from spreading through the breed.
breeds at risk
including Burmillas, Bombays and Tiffanies (longhaired Asians)
The fairly recent Chinchilla ancestry of many Asians means that
there is a significant risk of PKD in the breed.
Certain colours of Persian have been permitted as outcrosses for
many years and may have introduced the PKD gene.
Matings to various breeds were allowed in the past and may have
introduced the PKD gene.
Matings to various breeds, including Exotics, were permitted in
the past and may have introduced the PKD gene.
The mixed ancestry origin of this breed means that the gene could
have been introduced and there could have been further introductions
from outcrosses to produce the newer colours.
There is a risk of PKD due to the various breeds used in the development
(Oriental Longhairs, Javanese, Mandarins)
Although only Siamese, Balinese and Oriental outcrosses have been
permitted since 1991, prior to that there were various breeds
in the background, including unregistered cats.
These may not be mated to any other breeds, but there may have
been mixed matings, including Persian, in their distant background.
These may not be mated to any other breeds, but their recognition
through the 'novice class' system in Europe means that
some cats have an unknown background.
Although only Siamese outcrosses have been permitted since 1989,
there are known Persians and other breeds in the distant background,
so there is a risk that the PKD gene could have been introduced.
Siamese may be outcrossed to Orientals and there are also cats
of unknown origin in the background of most Siamese, so there
is a slight risk that PKD could have been introduced.
The Siamese ancestry means that there is a slight risk of PKD,
but the Burmese ancestry reduces the risk.
Although, traditionally, Turkish Vans have not been mated to any
other breeds, some imported cats have other breeds in their background
so there may be a risk of PKD.
low risk breeds
to their GCCF registration policies and the way in which they
have been bred traditionally, the risk in the following breeds
should be very low.
Updated November 2008